Michael Sandstrom, Ph.D.

About Dr. Sandstrom:

Dr. Sandstrom earned his doctorate in Neuroscience from Ohio State University in 1998 where he worked with a Parkinson’s disease animal model to explore age-dependent brain plasticity associated with the nigrostriatal dopamine system. During a subsequent postdoctoral fellowship with Dr. George Rebec at Indiana University in Bloomington he mastered techniques of single-unit neurophysiological recording and explored contributions of ascorbate to basal ganglia function. In his current position as an assistant professor of psychology and neuroscience at Central Michigan University he has resumed research in deteriorative diseases of the brain, exploring neurophysiological mechanisms underlying behavioral disruptions in a transgenic mouse model of Huntington’s disease. Dr. Sandstrom focuses research primarily on awake and freely moving animal models.

Publications

• Dunbar, G.L., Sandstrom, M.I., Rossingnol, J., and Lescaudron, L., (2006) Neurotrophic enhancers as therapy for behavioral deficits in rodent models of Huntington’s Disease: Use of gangliosides, substituted pyrimidines, and mesenchymal stem cells, Behavioral and Cognitive Neuroscience Reviews , 5(2), 63-79.
• Rebec, G.V., Witowski, S.R., Sandstrom, M.I., Rostand, R.D., and Kennedy, R.T., (2005) Extracellular ascorbate modulates cortically evoked glutamate dynamics in rat striatum • SHORT COMMUNICATION, Neuroscience Letters, 378(3), 166-170.
• Sandstrom, M.I., Nelson, C.L., and Bruno, J.P., (2003) Neurochemical correlates of sparing from motor deficits in rats depleted of striatal dopamine as weanlings, Developmental Psychobiology, 43, 373-383.
• Sandstrom, M.I. and Rebec, G.V., (2003) Characterization of striatal activity in conscious rats: Contribution of NMDA and AMPA/kainite receptors to both spontaneous and glutamate-driven firing, Synapse, 47, 91-100.