Dr. Justin Oh-Lee received his Ph.D. in 1995 from the University of California, Los Angeles (UCLA) in Psychology (Behavioral Neuroscience). He was a post-doctoral IRTA fellow from 1995-1999 and served as a research fellow from 1999-2001 at the Clinical Pharmacology section, Experimental Therapeutics Branch, NINDS, National Institutes of Health, Bethesda, Maryland, before coming to Central Michigan University.
Dr. Oh-Lee's principal research interests focus on the treatment of Parkinson's disease and other neurodegenerative disorders. The major goal of the laboratory is to uncover the underlying molecular, genetic, biochemical, and psychobiological abnormalities that produce clinical symptoms in neurodegenerative diseases such as Parkinson's, Alzheimer's, and Huntington's. The current emphasis is on interactions of dopamine and glutamate in regulating basal ganglia output neurons because of the relevance of these transmitters to the pathophysiology and treatment of neurodegenerative disease. Current projects include investigations of the pathogenesis of motor response complications associated with chronic levodopa therapy in Parkinson's disease.
Shim, W., Li W.Y., Nguyen, D.-T., Paik, M.J., Lee, C.W., Choi, K.R., Choi, D.-K., Shim, J.S., Kim, Y., Oh-Lee, J.D., Bang, O.Y., Lee, G. (2013) Proteomic analysis after human bone marrow-derived mesenchymal stem cell transplantation in ischemic rats. Molecular Cell Neuroscience
Eagle, A.L., Olumolade, O., Reischman, A., and Oh-Lee, J.D. (2013) Partial dopaminergic denervation-induced impairment in stimulus discrimination acquisition in parkinsonian rats: a model for presymptomatic Parkinson’s disease. Behavioral Brain Research
Assar, N., Reischman, A., Agauas, S., and Oh-Lee, J.D. (2013) Effect of dopamine transmission on anxiety level in Pitx3-deficient aphakia mice, a novel genetic model of Parkinson's disease. Behavioral Neuroscience
Oh-Lee, J.D. & Otani, H. (2013). Metamemory and Parkinson’s Disease. Tip of the Tongue States and Related Phenomena (Ed: Bennett Schwartz & Alan Brown), in press
Oh-Lee, J.D., Szymkowicz, S.M., Smith, S.L., & Otani, H. (2012). Metacognitive Performance, The Tip-Of-Tongue Experience, Is Not Disrupted In Parkinsonian Patients. Parkinson’s Disease, 2012, 12.
Wang, J., Teng, Y.-H., Hao, Y., Oh-Lee, J. D.-H., & Mohanty, D. K. (2009). Preparation and properties of polyamines: Part II-Controlled and sustained release of nitric Oxide (NO) from nitrosated polymers. The Society of Polymer Science, 41(9), 715-723.