The Nikon A1R is the new scanning laser confocal light microscope (CLSM). It is based on a Nikon Eclipse inverted microscope, and has Differential Interference Contrast (DIC) optics. The A1R is the primary research confocal microscope. This microscope uses a special detector for confocal scanning laser imaging, and also has a transmitted-light detector. Imaging capabilities include reflected-light confocal and transmitted-laser DIC imaging. It has 3 solid-state lasers and a dual-line argon gas laser, producing excitation lines at 403, 457/476, 488/514, 560 and 640 nm.

• BIO 553: Confocal Microscopy