For the last 20 years, I have been working on different aspects of normal and pathological aging (behavioral to molecular approaches), notably Alzheimer’s disease.

More recently I have been more focus on the role of inflammatory processes in the development of Alzheimer’s disease and trying to identify ways to target them.

We are currently actively looking at:

  • The role of early inflammation (pre-symptomatic) in the 5xFAD mouse model of Alzheimer’s disease.
  • The role of early systemic chronic inflammation in the regulation of amyloid plaques formation and neuronal structure in the NL-G-F knock-in mouse model of Alzheimer’s disease.

We are hoping that those projects will lead to a better understanding of the contribution of inflammatory processes in the neurodegenerative context that is Alzheimer’s disease.