facultystaffheader
 
​​Francisco J. Martinez

Foundational Sciences

Specialty: Pathology and Laboratory Medicine.

1280 S. East Campus Drive, CMED 1436
Mount Pleasant, MI 48859
marti1fj@cmich.edu
Phone: 989-774-6506​​
Fax: 989-774-1215
  


Francisco J. Martinez is an Associate Professor of Pathology in the Foundational Sciences at CMU CMED. He received his M.D. degree from the State University of San Luis Potosi, Mexico and Ph D. in experime​​ntal medicine (Dr. med) from the State University of Nuevo Leon, Mexico, where he characterized the action of peroxisomicine A1 (PA1), a dimeric-anthracenone natural compound, in normal eucariotic and malignant cell lines from the ATCC through apoptosis induction and its effects on cell cycle events. This was followed by the search of specific targets and known pathways of apoptosis, in HL60 and HL60/MX2 cells derived of human leukemia and confirming apoptosis by DNA degradation with fluorochrome stains and in FACScan as well as selective targets of apoptosis: DNA topoisomerase II; PARP; caspase 3 and 8 by cell and molecular biology methods, aiming to the possible development of chemotherapeutic agents for either PA1 radical metabolites alone or in combination.

His longstanding career as medical educator started as a trainee at a large referral medical center in Mexico City in Human Pathology and in Anatomic and Clinical Pathology at Saint John Hospital and Medical Center in Detroit, MI., followed by pathology faculty and research positions once back in Mexico City and Monterrey City and in American International University medical schools, imparting the knowledge of disease to medical colleagues, medical undergraduates and trainees at all levels. He also developed as consultant physician practicing pathology and laboratory medicine in hospital and clinical laboratories.

Education & Fellowships:
  • Doctorate
    • The San Luis Potosi State University of Mexico
      M.D., Human Medicine
    • The Nuevo Leon State University
      Ph D., Experimental Medicine
      Monterrey Mexico
  • Residence
    • ​Saint John Hospital and Medical Center
      Pathology: AP, CP, EP
      Detroit, MI
  • Internal Medicine/Surgery
    • Saint John Hospital and Medical Center
      Flexible PGY1
      Detroit, MI
  • Human Pathology
    • National Medical Center - 'ISSSTE 20 de Noviembre' and UNAM (The National University)
      Mexico City
  • Visiting Professor
    • Case Western Reserve University, Division of General Medical Sciences - Center for Medical Education
      Cleveland, OH
  • Harvard Macy Scholar
    • Harvard Macy Institute of Harvard University Medical School
      Boston, MA
  • Visiting Research Scientist
    • INSERM. U 524-et Centre Oscar Lambret,
      Laboratorie du Pharmacologie Antitumorale,
      Lille Cedex, France
    • LXR Biotechnology Inc.
      Richmond, CA
    • 'Meyer L. Prentis' Cancer Center (Michigan Cancer Foundation, MCF
      Detroit, MI
    • Comprehensive Cancer Center and The Engeneering Society
      Fellowship on Environmental Carcinogenesis
      Detroit, MI
      (Scholarship of the Ford Motor Co.)
    • The Jackson Laboratory
      Fellow of First UICC-USA Course in Cancer Research
      Bar Harbor, ME
    • The Frank Fitzsimmons Experimental Surgery Unit
      Pontiac, MI
Certifications:
  • ECFMG 177-962-8; ASCP A-55357
Specialty Interests:
Medical education; biomedical and scientific research methodology and EBM; translational research.

Awards & Honors:
  • Researcher Recognition Award, 2003
    • The State University of Nuevo Leon, Faculty of Medicine (Postrgaduate - Research Secretariat Award).
  • Annual Scientific Seminar Award 1980 and 1979
    • Saint John Hospital and Medical Center, Detroit, MI.
  • Honorary Scholarship, 1993 - 1997
    • Ph D program, (CoNaCyT- Mexico).
  • American Medical Association Award, C.M.E. 1982.
  • Honorary Scholarship for MD career program
    • The State University of San Luis Potosi, Mexico -Tutor´s Association, 1965 -1970.
Clinical Research Awards:
  • National Annual Meeting of Biomedical Research (UANL- Faculty of Medicine). Monterrey, N.L., México: 1997, 1992 and 1989.
Memberships:
  • International Association for Medical Schools Educators, (IAMSE).
  • American Association for the Advancement of Science, (AAAS).
  • American Society for Clinical Pathology, (ASCP).
Language Spoken:
  • English, Spanish
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