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Choon Lee

​​​Professor
Organic Chemistry
Dow Science Complex 338
989-774-3289
​​Educ​ation
  • Ph.D., Biomedical Sciences, concentration in Medicinal Chemistry, Northeastern University, 2000
  • M.S., Biomedical Sciences, concentration in Medicinal Chemistry, Northeastern University, 1997
Affiliations
American Chemical Society
Professional Interests
Investigation of anti-cancer agents; Synthesis of antioxidant dendrimers for biological applications.
Teaching Areas
Organic Chemistry I and II, Intermediate Organic Chemistry, Organic Reactions and Synthesis
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Selected Publications and Presentations
  • ​​Lee, C.Y.; Sharma, A.; Cheong, J.E.; Nelson, J.E. Synthesis and antioxidant properties of dendritic polyphenols. Bioorg. Med. Chem. Lett. 2009, 19(22), 6326-6330.
  • Lee, C.Y.; Ki, D.W.; Sharma, A. Method for amine-amine attachment in nanodevice preparation. J. Mater. Sci. 2009, volume 44 (12), 3179-3185.
  • Stuart, A.; McCallum, M.M.; Fan, D.; LeCaptain, D.J.; Lee, C.Y.; Mohanty, D.K. Poly(vinyl chloride) plasticized with succinate esters- Synthesis and characterization. Polym. Bull. (In press).
  • Dendritic nano-antioxidants, US Provisional Patent No61/164,041, 2009. 
  • Desai, A.; Lee, C.; Sharma, L.; Sharma, A. Lysozyme refolding with cyclodextrins: Structure activity relationship. Biochimie, 2006, 88, 1435-1445.
  • Hanson, R.N.; Lee, C.Y.; Friel, C. "Novel steroidal anti-estrogens and anti-androgens and uses thereof". 2006, Patent No: 7,041,839.
  • Hanson, R.N.; Lee, C.Y.; Friel, C.; Dillis, R.;  Hughes, A.; DeSombre, E. Synthesis and evaluation of 17α-20E-21-(4-substituted phenyl)-19-norpregna-1,3,5(10),20-tetraene-3,17β-diols as probes for the estrogen receptor α hormone binding domain. J. Med. Chem. 2003, 46, 2865-2876.
  • Hanson, R.N.; Lee, C.Y.; DeSombre, E.; Hughes, A. Evaluation of 17a-E-(trifluoromethyl phenyl) vinyl estradiols as novel estrogen receptor ligands. Steroids, 2003, 68(2), 143-148.
  • Sebag, A.; Hanson, R.N.; Forsyth, D.; Lee, C.Y. Conformational studies of novel estrogen receptor ligands by 1D and 2D NMR spectroscopy and computational methods. Magn. Reson. Chem. 2003, 41, 246-252.
  • Lee, C.Y.; Hanson, R.N. Solid Phase Synthesis of 17a-E/Z-(X-phenyl)-vinyl estradiols using the Stille coupling reaction. Tetrahedron, 2000, 56, 1623-1629.

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