David Ash
David Ash Professor and Department Chairperson
Dow Science Complex 268

  • Ph.D., Biophysics, University of Pennsylvania, 1982
  • B.S., Chemistry, Pennsylvania State University, 1974
American Chemical Society; American Society for Biochemistry and Molecular Biology; Society of Biological Inorganic Chemistry
Honors and Awards
  • Chemistry Professor of the Year (CMU), 2006
  • Temple University Million Dollar Club, 2005
  • Academy of Distinguished Educators in Medicine, 2004
  • Lindback Award for Distinguished Teaching (Temple University School of Medicine), 2000
  • Golden Apple Teaching Award (Temple University School of Medicine): 1988, 1990, 1994, 2005
Professional Interests
Enzyme reaction mechanisms, role of inorganic cofactors in enzyme-catalyzed reactions, enzymes of arginine metabolism.
​​Teaching Areas
Biochemistry, General Chemistry
​​Selected Publications and Presentations
  • Rodriguez, S.B., Stitt, B.S., and Ash, D.E., “Expression of Peptidylarginine Deiminase from Porphyromo​nas gingivalis in Escherichia coli; Enzyme Purification and Characterization.  Sofía B. Rodríguez, Barbara L. Stitt, and David E. Ash, in press.
  • Shishova E. Y., Di Costanzo, L., Emig, F.A., Ash, D.E., and Christianson, D.W., “Probing the Specificity Determinants of Amino Acid Recognition by Arginase”, Biochemistry 48, 121-131 (2009).
  • Ash, D.E., “Arginase: New Functions for an Old Enzyme”, Michigan State University, 2008.
  • Colleluori, D.M., Reczkowski R.S., Emig, F.A., Cama, E., Cox, J.D., Scolnick, L.R., Compher,K., Jude K., Han, S., Viola, R.E., Christianson D.W.,  Ash, D.E.,  “Probing the Role of the Hyper-reactive Histidine Residue of Arginase”, Arch. Biochem. Biophys. 444, 15-26 (2005). 
  • Ash, D. E. “Structure and Function of Arginases”, J. Nutr. 134, 2760S-2764S (2004).​