Skip navigation

Mary Tecklenburg

Mary Tecklenburg

Dow Science Complex 353


Postdoc., Biophysical Chemistry, Michigan State University, 1990
Ph.D., Physical Chemistry, Texas A&M University, 1989
M.S., Indiana University, Purdue University at Indianapolis, 1983
B.S., Chemistry, St. Louis University, 1982

Research Fields

  • Raman and IR spectroscopy of materials
  • Molecular structure and transformation

Current Research Projects

  • In my research, vibrational spectroscopy is used to solve problems dealing with molecular structure. Nearly any type of sample can be analyzed by Raman spectroscopy because of the flexibility of using a focused laser beam as the light source. My current focus is on apatite, a form of calcium phosphate, which is the major constituent of bone and is also found as a natural mineral in rocks. A better understanding of the initial formation and aging of bone and its response to stress is important for improving health. We are making apatite substituted with ions typically found in bone in order to support bone tissue studies. The transformations among crystalline and amorphous forms of calcium phosphates are studied as models of early mineralization. The affect of pressure on bone strength is another area of interest. The nucleation and growth of apatite on silicate surfaces as applied to bone implants are being studied. In another project we are studying the silane hydrolysis process, developing a Raman detection method and studying the kinetics of the process. The materials I study are diverse and have also included proteins containing the heme group (hemoglobin and cytochrome oxidase), inorganic glasses (germanium diselenide doped with metals) and polymers (azoaromatic polyethers). Modern computational modeling of molecular structure and conformation augments my experimental studies.

Selected Publications

  • J. Xu, P. Zhu, Z. Gan, N. Sahar, M. J. Tecklenburg, M. D. Morris, D. H. Kohn, and A. Ramamoorthy. “Natural-Abundance 43Ca Solid State NMR Spectroscopy of Bone,” Journal of the American Chemical Society, 2010, 132, 11504-11509.
  • M. J. Tecklenburg and B. Whitman, “Raman Spectroscopy of Bone Mineral Crystallization in a Microfluidic Chip,” Proceedings of the XXII International Conference on Raman Spectroscopy, P. Champion, L. Ziegler, Eds., Vol. 1267, American Institute of Physics, 2010, pp. 412-413.
  • B. Pavan, D. Zhou, B. Whitman, M. Fornari and Mary Tecklenburg, “Bone Bio-Mineralization: in Depth Analysis of Hydroxylapatite Crystallization Through Experiments and Simulations,” Proceedings of the XXII International Conference on Raman Spectroscopy, P. Champion, L. Ziegler, Eds., Vol. 1267, American Institute of Physics, 2010, pp. 344-345.
  • Ayorinde Awonusi, Michael D. Morris, Mary M. J. Tecklenburg, “Carbonate Assignment and Calibration in the Raman Spectrum of Apatite” Calcified Tissue International, 2007, 81, 46-52.
  • E. E. Wilson, Ayorinde Awonusi, M. D.Morris, D. H. Kohn, M. M. J. Tecklenburg, L. Beck, “Three Structural Roles of Water in Bone Observed by Solid-State NMR” Biophysical Journal, 2006, 90, 3722-3731.
  • V. Carmejane, M. D. Morris, M. K. Davis, L. Stixrude, M. Tecklenburg, R. M. Rajachar and D. H. Kohn, “Bone Chemical Structure Response to Mechanical Stress Studied by High Pressure Raman Spectroscopy,” Calcified Tissue International, 2005, 76, 207-213.
  • Erin Wilson, Ayorinde Awonusi, Micha= el Morris, David Kohn, Mary Tecklenburg, Larry Beck, “Highly Ordered Interstitial Water Observed in Bone by Nuclear Magnetic Resonance,”Journal of Bone and Mineral Research, 2005, 20, 625-634.
  • Mary M. J. Tecklenburg, Elisabeth Larsen, Bogdan Lita, Didarul I. Qadir, “Effect of Copper on the Local Structure of GeSe2Cux Probed by Raman Spectroscopy,” Journal of Non-Crystalline Solids, 2003, 328, 40-47.
  • M. J. Tecklenburg, Derek Kosnak, Atul Bhatnagar and Dillip Mohanty, "Vibrational Characterization of Azobenzenes, Azoxybenzenes and Azoaromatic and Azoxyaromatic Polyethers," Journal of Raman Spectroscopy, 1997, 28, 755-763.

CMU is an AA/EO institution, providing equal opportunity to all persons, including minorities, females, veterans and individuals with disabilities. | CentralLink
Copyright Central Michigan University, Mount Pleasant, Mich. 48859 | Phone 989-774-4000 | Privacy Policy | Website Feedback