Dr. Sharma is a professor in the Department of Chemistry & Biochemistry at Central Michigan University
Education
- Ph.D., Wayne State University School of Medicine, 1983-1987
- M.S., University of Windsor, 1983
- B.S/M.S., Panjab University, 1977
Affiliations
- American Chemical Society
- American Association of Pharmaceutical Scientists
Honors & Awards
- CMU Excellence in Teaching Award, 1993,
- American Chemical Society Outstanding Achievement in College Chemistry Teaching, 1993
Professional Interests
- Characterization of Dendritic Nanomolecules with Bioanalytical Techniques
- Chemical Education: Dendrimers in Biology and Medicine
Teaching Areas
- General Chemistry
- Biochemistry
- Bioanalytical Chemistry
Publications
- 2017 SM Brockman, M Bodas, D Silverberg, A
Sharma, N. Vij. Dendrimer-based selective autophagy-induction rescues ∆F508-CFTR and inhibits Pseudomonas aeruginosa infection in cystic fibrosis
PLoS One. 2017 September 13.doi.org/10.1371
- 2017 Srinageshwar B, Peruzzaro S, Andrews M, Johnson K, Hietpas A, Clark B, McGuire C, Petersen E, Kippe J, Stewart A, Lossia O, Al-Gharaibeh A, Antcliff A, Culver R, Swanson D, Dunbar GL,
Sharma A, Rossignol J. PAMAM Dendrimers Cross the Blood-Brain Barrier When Administered through the Carotid Artery in C57BL/6J Mice.
Int J Mol Sci., 2017 Mar 14; 18(3), 628. PMID: 28335421 PMCID: PMC5372641.
- 2016 K Walworth, M Bodas, RJ Campbell, D Swanson, A
Sharma, N. Vij. Dendrimer-based selective proteostasis-inhibition strategy to control NSCLC growth and progression
PLoS One. 2016 19;11(7):e0158507.doi:10.1371
- 2014 Samik Upadhaya, DR Swanson, DA Tomalia, A.
Sharma. Analysis of polyamidoamine dendrimers by isoelectric focusing.
Anal Bioanal Chem 406, 455-458
- 2011 Choon Young Lee, Ajit
Sharma, Rebecca L. Uzarski, Jae Eun Cheong, Hao Xu, Rich A. Held, Samik K. Upadhaya, and Julie L. Nelson. Potent antioxidant dendrimers lacking pro-oxidant activity.
Free Radical Biology and Medicine. 50, 918-925.
- 2009 Lee Choon Young,
Sharma Ajit, Cheong Jae Eun, Nelson Julie L. Synthesis and antioxidant properties of dendritic polyphenols. Bioorganic & medicinal chemistry letters. 19, 6326-6330. 2009.
- C.Lee D.W. Woo, A.
Sharma. Method for amine-amine attachment in nanodevices preparation.
J. Mater Sci 44, 3179.
- 2007. Britton Carter, Ankur Desai, Ajit
Sharma. Use of polyvinyl alcohol-coated capillaries for separation of amino terminated polyamidoamine dendrimers. Electrophoresis 28, 335.
- 2006. S. Tang, LJ Martinez, A.
Sharma, M. Chai. Synthesis and characterization of water-soluble and photostable L-Dopa dendrimers.
Organic Letters 8, 4421.
- 2006. Ankur Desai, Loretta Sharma, Choon Lee, Ajit
Sharma. Lysozyme refolding with cyclodextrins: Structure activity relationship.
Biochimie 88, 1435.
- 2006. Loretta Sharma, Ankur Desai, Ajit
Sharma. A Thin Layer Chromatography Laboratory Experiment of Medical Importance.
Biochemistry and Molecular Biology Education, 34, 44-48.
- 2006. Teng, Y, Kaminski GA, Zhang, Z,
Sharma A, Mohanty DK. Preparation of polyamines. Part I. Polymers containing dinitro substituted aromatic groups. Polymer, 47, 4004-4 1.
- 2005.
Sharma, A, Desai A and Ali R, Tomalia, D. Polyacrylamide gel electrophoresis separation and detection of polyamidoamine dendrimers possessing various cores and terminal groups.
J Chromatography A, 1081, 238-244.
- 2005.
Sharma A, Rao, M., Miller, R, Desai. Fluorometric assay for detection and quantitation of polyamidoamine dendrimers.
Anal. Biochem. 2 4, 70-75.
- 2003.
Sharma A, Mohanty DK, Desai A and Ali R. A simple polyacrylamide gel electrophoresis procedure for the separation of polyamidoamine dendrimers.
Electrophoresis 24, 2733-2739.
- 2001. Sharma L and
Sharma A. Influence of ring substituents on folding-relatedaggregation of bovine carbonic anhydrase.
Eur. J. Biochem. 268, 2456.