Choon Lee
Professor
Department of Chemistry & Biochemistry
Organic Chemistry
Dow Science Complex 338
989-774-3289


Dr. Lee is a professor of Chemistry & Biochemistry at Central Michigan University

Affiliations

  • American Chemical Society

Education

  • Ph.D., Biomedical Sciences, concentration in Medicinal Chemistry, Northeastern University, 2000 
  • M.S., Biomedical Sciences, concentration in Medicinal Chemistry, Northeastern University, 1997​

Professional Interests

  • Investigation of anti-cancer agents
  • Synthesis of antioxidant dendrimers for biological applications

Teaching Areas

  • Organic Chemistry I and II
  • Intermediate Organic Chemistry
  • Organic Reactions and Synthesis

Research is currently being conducted in my lab to describe pollen grain diversity across the Brassicaceae. Trends in pollen evolution will be examined relative to recent advances in phylogenetic reconstruction and tribal classifications within the family. Pollen morphological data from scanning electron and light microscopy will be used to examine pollen evolutionary patterns and correlated floral evolution across the Brassicaceae.

Publications

  • Lee, C.Y.; Sharma, A.; Cheong, J.E.; Nelson, J.E. Synthesis and antioxidant properties of dendritic polyphenols. Bioorg. Med. Chem. Lett. 2009, 19(22), 6326-6330. 
  • Lee, C.Y.; Ki, D.W.; Sharma, A. Method for amine-amine attachment in nanodevice preparation. J. Mater. Sci. 2009, volume 44 (12), 3179-3185. 
  • Stuart, A.; McCallum, M.M.; Fan, D.; LeCaptain, D.J.; Lee, C.Y.; Mohanty, D.K. Poly(vinyl chloride) plasticized with succinate esters- Synthesis and characterization. Polym. Bull. (In press). Dendritic nano-antioxidants, US Provisional Patent No: 61/164,041, 2009. 
  • Desai, A.; Lee, C.; Sharma, L.; Sharma, A. Lysozyme refolding with cyclodextrins: Structure activity relationship. Biochimie, 2006, 88, 1435-1445. 
  • Hanson, R.N.; Lee, C.Y.; Friel, C. "Novel steroidal anti-estrogens and anti-androgens and uses thereof". 2006, Patent No: 7,041,839
  • Hanson, R.N.; Lee, C.Y.; Friel, C.; Dillis, R.; Hughes, A.; DeSombre, E. Synthesis and evaluation of 17α-20E-21-(4-substituted phenyl)-19-norpregna-1,3,5(10),20-tetraene-3,17β-diols as probes for the estrogen receptor α hormone binding domain. J. Med. Chem. 2003, 46, 2865-2876. 
  • Hanson, R.N.; Lee, C.Y.; DeSombre, E.; Hughes, A. Evaluation of 17a-E-(trifluoromethyl phenyl) vinyl estradiols as novel estrogen receptor ligands. Steroids, 2003, 68(2), 143-148. 
  • Sebag, A.; Hanson, R.N.; Forsyth, D.; Lee, C.Y. Conformational studies of novel estrogen receptor ligands by 1D and 2D NMR spectroscopy and computational methods. Magn. Reson. Chem. 2003, 41, 246-252. 
  • Lee, C.Y.; Hanson, R.N. Solid Phase Synthesis of 17a-E/Z-(X-phenyl)-vinyl estradiols using the Stille coupling reaction. Tetrahedron, 2000, 56, 1623-1629.