Wang, Xia
M.D., Ph.D.
Biography
Dr. Wang is a clinical medical geneticist with accreditations from the American Board of Medical Genetics and Genomics (ABMGG) and the American Board of Internal Medicine (ABIM). She has 20 years of experience in genetic conditions. In her career, she has provided diagnosis and care for adults and children across the entire spectrum of medical genetics, including but not limited to cancer genetics, cardiogenetics, neurogenetics, genetic syndromes, genetic conditions associated with chromosomal abnormalities, single-gene mutations, and dysmorphology. Her main focuses are the evaluation of hereditary cancer, interpretation of genetic test results, cancer screening for individuals with hereditary risk, and comprehensive care for individuals with complex hereditary tumor syndromes, such as neurofibromatosis, tuberose sclerosis, Cowden syndrome, Li-Fraumeni syndrome, and von Hippel-Lindau disease. In her previous posts in Henry Ford Health System and Moffitt Cancer Center, Dr. Wang created and directed a multi-disciplinary neurofibromatosis clinic. Dr. Wang is enthusiastic about teaching and is determined to promote medical genetics awareness to improve diagnostic accuracy and quality of care through medical genetics education.
More about Xia Wang
Publications & Presentations
Moore C, Bao Y (2022). Benign Goiters Requiring Thyroidectomy as The Signal for PTEN Hamartoma Tumor Syndrome Diagnosis Am J Med Genet A.
Wang X (2022). Orthopaedic Manifestations of Neurofibromatosis Journal of the American Academy of Orhtopaedic Surgeons.
Chang MD, Lee MC, Niell BL (2022). The Breast Cancer Screening and Timing of Breast MRI – Experience in A Genetic High-Risk Screening Clinic in A Comprehensive Cancer Center Current Oncology.
Wei G, Teng M, Rosa M, Wang X (2022). Unique ER PR expression pattern in breast cancers with CHEK2 mutation: a hormone receptor and HER2 analysis based on germline cancer predisposition genes. Breast cancer research : BCR.
Nocera N, Moore C, Chang MD, Lee MC, Wang X (2022). GeneHome -- A Novel Model to Deliver Care to Individuals with Genetic Predisposition to Cancer Cancer Control.
Wang X, Chang MD, Lee MC, Niell BL (2022). The Breast Cancer Screening and Timing of Breast MRI-Experience in a Genetic High-Risk Screening Clinic in a Comprehensive Cancer Center. Current oncology (Toronto, Ont.).
Wei G, Kumar A, Lee MC, Wang X (2021). Influential Factors on Risk-reduction Mastectomy in a High-risk Breast Cancer Population With Genetic Predispositions. Clinical breast cancer.
Galati MA, Hodel KP, Gams MS, Sudhaman S, Bridge T, Zahurancik WJ, Ungerleider NA, Park VS, Ercan AB, Joksimovic L, Siddiqui I, Siddaway R, Edwards M, de Borja R, Elshaer D, Chung J, Forster VJ, Nunes NM, Aronson M, Wang X, Ramdas J, Seeley A, Sarosiek T, Dunn GP, Byrd JN, Mordechai O, Durno C, Martin A, Shlien A, Bouffet E, Suo Z, Jackson JG, Hawkins CE, Guidos CJ, Pursell ZF, Tabori U (2020). Cancers from Novel Pole-Mutant Mouse Models Provide Insights into Polymerase-Mediated Hypermutagenesis and Immune Checkpoint Blockade. Cancer research.
Berry DK, Wang X, Michalski ST, Kang HC, Yang S, Creelan BC, McLeod HL, Hicks JK (2020). Clinical Cohort Analysis of Germline EGFR T790M Demonstrates Penetrance Across Ethnicities and Races, Sexes, and Ages. JCO precision oncology.
Miller DT, Cortés-Ciriano I, Pillay N, Hirbe AC, Snuderl M, Bui MM, Piculell K, Al-Ibraheemi A, Dickson BC, Hart J, Jones K, Jordan JT, Kim RH, Lindsay D, Nishida Y, Ullrich NJ, Wang X, Park PJ, Flanagan AM (2020). Genomics of MPNST (GeM) Consortium: Rationale and Study Design for Multi-Omic Characterization of NF1-Associated and Sporadic MPNSTs. Genes.
Wang X, Chitale D (2019). HER2 Expression in NF1 Breast Cancer-Response. Cancer prevention research (Philadelphia, Pa.).
Wang X, Brzosowicz JP, Park JY (2019). Response to Roberts et al. 2018: cohort ascertainment and methods of analysis impact the association between cancer and genetic predisposition - the tale of breast cancer risk and Lynch syndrome genes MSH6/PMS2. Genetics in medicine : official journal of the American College of Medical Genetics.
Wang X, Kallionpää RA, Gonzales PR, Chitale DA, Tousignant RN, Crowley JP, Chen Z, Yoder SJ, Blakeley JO, Acosta MT, Korf BR, Messiaen LM, Tainsky MA (2018). Germline and Somatic NF1 Alterations Are Linked to Increased HER2 Expression in Breast Cancer. Cancer prevention research (Philadelphia, Pa.).
Wang X, Teer JK, Tousignant RN, Levin AM, Boulware D, Chitale DA, Shaw BM, Chen Z, Zhang Y, Blakeley JO, Acosta MT, Messiaen LM, Korf BR, Tainsky MA (2018). Breast cancer risk and germline genomic profiling of women with neurofibromatosis type 1 who developed breast cancer. Genes, chromosomes & cancer.
Tousignant RN, Levin AM, Niell B, Blakeley JO, Acosta MT, Korf BR (2016). Indicator Exploration for Cancers in Women with Neurofibromatosis Type 1 - A Multi-Centre Retrospective Study Journal of Genetic Syndromes & Gene Therapy.
Wang X, Levin AM, Smolinski SE, Vigneau FD, Levin NK, Tainsky MA (2012). Breast cancer and other neoplasms in women with neurofibromatosis type 1: a retrospective review of cases in the Detroit metropolitan area. Am J Med Genet A..
Wooderchak W, Gedge F, McDonald M, Krautscheid P, Wang X, Malkiewicz J, Bukjiok CJ, Lewis T and Bayrak-Toydemir P (2010). Hereditary hemorrhagic telangiectasia: two distinct ENG deletions in one family Clin. Genet..
Wang X, Jakobs C, Bawle EV (2003). Hydroxyglutaric aciduria with absence of corpus callosum and neonatal intracranial haemorrhage. J Inherit Metab Dis..
Wang X, Hansen SK, Ratts R, Zhou S, Snook AJ, Zehring W (1997). Drosophila TFIIE: Purification, cloning, and functional reconstitution Proc Natl Acad Sci U S A..
Drescher D.G., Ramakrishnan N.A., Chun W., Wang X., Green G.E., Karpenko A.N., Drescher M. J., and Myers S.F. (1996). Rainbow trout saccular hair cell epithelium alpha 9 nicotinic acetylcholine receptor (nAChR) subunit cDNA, complete coding sequence AY037940 Genebank.
Education
Membership in Professional Organizations
AMA
Saginaw County Medical Society (SCMS)