Bakke, Jesse
Ph.D.
Associate Professor
Biography
At the Central Michigan University College of Medicine, Jesse Bakke, Ph.D., plays an active role in educating medical students within the preclinical curriculum. He teaches in the areas of nutrition, biochemistry and oncology, and serves as course director for the Digestive and Excretory course. Bakke regularly leads Peer Instruction, Team-Based Learning, and Problem-Based Learning sessions. His teaching philosophy is to make complex subject material approachable and relevant to the students. Bakke’s educational scholarship focuses on the use of innovative pedagogical methods to improve student motivation and understanding of challenging subjects, particularly biochemistry. He currently serves in leadership roles in the Association of Biochemistry Educators. In addition to his education scholarship, he also has an active research lab.
More about Jesse Bakke
Publications & Presentations
Albosta M, Bakke J (2021). Intermittent fasting: is there a role in the treatment of diabetes? A review of the literature and guide for primary care physicians. Clinical diabetes and endocrinology.
Oladimeji PO, Bakke J, Wright WC, Chen T (2020). KANSL2 and MBNL3 are regulators of pancreatic ductal adenocarcinoma invasion. Scientific reports.
Bakke J, Wright WC, Zamora AE, Oladimeji P, Crawford JC, Brewer CT, Autry RJ, Evans WE, Thomas PG, Chen T (2019). Genome-wide CRISPR screen reveals PSMA6 to be an essential gene in pancreatic cancer cells. BMC cancer.
Zamora AE, Crawford JC, Allen EK, Guo XJ, Bakke J, Carter RA, Abdelsamed HA, Moustaki A, Li Y, Chang TC, Awad W, Dallas MH, Mullighan CG, Downing JR, Geiger TL, Chen T, Green DR, Youngblood BA, Zhang J, Thomas PG (2019). Pediatric patients with acute lymphoblastic leukemia generate abundant and functional neoantigen-specific CD8+ T cell responses. Science translational medicine.
Li Y, Bakke J, Finkelstein D, Zeng H, Wu J, Chen T (2018). HNRNPH1 is required for rhabdomyosarcoma cell growth and survival. Oncogenesis.
Bakke J, Wright WC, Zamora AE, Ong SS, Wang YM, Hoyer JD, Brewer CT, Thomas PG, Chen T (2017). Transcription factor ZNF148 is a negative regulator of human muscle differentiation. Scientific reports.
Vitorino P, Yeung S, Crow A, Bakke J, Smyczek T, West K, McNamara E, Eastham-Anderson J, Gould S, Harris SF, Ndubaku C, Ye W (2015). MAP4K4 regulates integrin-FERM binding to control endothelial cell motility. Nature.
Bakke J, Haj FG (2015). Protein-tyrosine phosphatase 1B substrates and metabolic regulation. Seminars in cell & developmental biology.
Borkowski K, Wrzesinski K, Rogowska-Wrzesinska A, Audouze K, Bakke J, Petersen RK, Haj FG, Madsen L, Kristiansen K (2014). Proteomic analysis of cAMP-mediated signaling during differentiation of 3 T3-L1 preadipocytes. Biochimica et biophysica acta.
Bakke J, Bettaieb A, Nagata N, Matsuo K, Haj FG (2013). Regulation of the SNARE-interacting protein Munc18c tyrosine phosphorylation in adipocytes by protein-tyrosine phosphatase 1B. Cell communication and signaling : CCS.
Bettaieb A, Bakke J, Nagata N, Matsuo K, Xi Y, Liu S, AbouBechara D, Melhem R, Stanhope K, Cummings B, Graham J, Bremer A, Zhang S, Lyssiotis CA, Zhang ZY, Cantley LC, Havel PJ, Haj FG (2013). Protein tyrosine phosphatase 1B regulates pyruvate kinase M2 tyrosine phosphorylation. The Journal of biological chemistry.
Nagata N, Matsuo K, Bettaieb A, Bakke J, Matsuo I, Graham J, Xi Y, Liu S, Tomilov A, Tomilova N, Gray S, Jung DY, Ramsey JJ, Kim JK, Cortopassi G, Havel PJ, Haj FG (2012). Hepatic Src homology phosphatase 2 regulates energy balance in mice. Endocrinology.
Bettaieb A, Liu S, Xi Y, Nagata N, Matsuo K, Matsuo I, Chahed S, Bakke J, Keilhack H, Tiganis T, Haj FG (2011). Differential regulation of endoplasmic reticulum stress by protein tyrosine phosphatase 1B and T cell protein tyrosine phosphatase. The Journal of biological chemistry.
Franke AA, Morrison CM, Bakke JL, Custer LJ, Li X, Cooney RV (2010). Coenzyme Q10 in human blood: native levels and determinants of oxidation during processing and storage. Free radical biology & medicine.
Oladimeji PO, Bakke J, Wright WC, Chen T (2020). KANSL2 and MBNL3 are regulators of pancreatic ductal adenocarcinoma invasion. Scientific reports.
Bakke J, Wright WC, Zamora AE, Oladimeji P, Crawford JC, Brewer CT, Autry RJ, Evans WE, Thomas PG, Chen T (2019). Genome-wide CRISPR screen reveals PSMA6 to be an essential gene in pancreatic cancer cells. BMC cancer.
Zamora AE, Crawford JC, Allen EK, Guo XJ, Bakke J, Carter RA, Abdelsamed HA, Moustaki A, Li Y, Chang TC, Awad W, Dallas MH, Mullighan CG, Downing JR, Geiger TL, Chen T, Green DR, Youngblood BA, Zhang J, Thomas PG (2019). Pediatric patients with acute lymphoblastic leukemia generate abundant and functional neoantigen-specific CD8+ T cell responses. Science translational medicine.
Li Y, Bakke J, Finkelstein D, Zeng H, Wu J, Chen T (2018). HNRNPH1 is required for rhabdomyosarcoma cell growth and survival. Oncogenesis.
Bakke J, Wright WC, Zamora AE, Ong SS, Wang YM, Hoyer JD, Brewer CT, Thomas PG, Chen T (2017). Transcription factor ZNF148 is a negative regulator of human muscle differentiation. Scientific reports.
Vitorino P, Yeung S, Crow A, Bakke J, Smyczek T, West K, McNamara E, Eastham-Anderson J, Gould S, Harris SF, Ndubaku C, Ye W (2015). MAP4K4 regulates integrin-FERM binding to control endothelial cell motility. Nature.
Bakke J, Haj FG (2015). Protein-tyrosine phosphatase 1B substrates and metabolic regulation. Seminars in cell & developmental biology.
Borkowski K, Wrzesinski K, Rogowska-Wrzesinska A, Audouze K, Bakke J, Petersen RK, Haj FG, Madsen L, Kristiansen K (2014). Proteomic analysis of cAMP-mediated signaling during differentiation of 3 T3-L1 preadipocytes. Biochimica et biophysica acta.
Bakke J, Bettaieb A, Nagata N, Matsuo K, Haj FG (2013). Regulation of the SNARE-interacting protein Munc18c tyrosine phosphorylation in adipocytes by protein-tyrosine phosphatase 1B. Cell communication and signaling : CCS.
Bettaieb A, Bakke J, Nagata N, Matsuo K, Xi Y, Liu S, AbouBechara D, Melhem R, Stanhope K, Cummings B, Graham J, Bremer A, Zhang S, Lyssiotis CA, Zhang ZY, Cantley LC, Havel PJ, Haj FG (2013). Protein tyrosine phosphatase 1B regulates pyruvate kinase M2 tyrosine phosphorylation. The Journal of biological chemistry.
Nagata N, Matsuo K, Bettaieb A, Bakke J, Matsuo I, Graham J, Xi Y, Liu S, Tomilov A, Tomilova N, Gray S, Jung DY, Ramsey JJ, Kim JK, Cortopassi G, Havel PJ, Haj FG (2012). Hepatic Src homology phosphatase 2 regulates energy balance in mice. Endocrinology.
Bettaieb A, Liu S, Xi Y, Nagata N, Matsuo K, Matsuo I, Chahed S, Bakke J, Keilhack H, Tiganis T, Haj FG (2011). Differential regulation of endoplasmic reticulum stress by protein tyrosine phosphatase 1B and T cell protein tyrosine phosphatase. The Journal of biological chemistry.
Franke AA, Morrison CM, Bakke JL, Custer LJ, Li X, Cooney RV (2010). Coenzyme Q10 in human blood: native levels and determinants of oxidation during processing and storage. Free radical biology & medicine.
Credentials, Certifications & Awards
NIH Biotechnology Training Fellowship
Nutritional biology Graduate Student Fellowship
Peter J. Shields and Henry A. Jastro Research Award
UCD and Humanities Graduate Research Award
Nutritional biology Graduate Student Fellowship
Peter J. Shields and Henry A. Jastro Research Award
UCD and Humanities Graduate Research Award
Education
Ph.D., University of California-Davis, Davis
Baccalaureate, University of Hawaii at Manoa
Post-doctoral Fellowship, St. Jude Children's Research Hospital, Memphis, Tennessee (TN)
Baccalaureate, University of Hawaii at Manoa
Post-doctoral Fellowship, St. Jude Children's Research Hospital, Memphis, Tennessee (TN)
Membership in Professional Organizations
American Heart Association
AACR
Association of Biochemistry Educators
AACR
Association of Biochemistry Educators